Nimesulide - Uses - Dosages - Side Effects - Precautions

Nimesulide: Frequently Asked Questions Answered

What is Nimesulide?

Nimesulide is a Cox -II Inhibitor in human bodies. Cox II is an enzyme mainly responsible for causing inflammation in a disease or other conditions. Nimesulide being a Cox- II inhibitor, acts as an anti-inflammatory agent. It is a non-steroidal anti-inflammatory drug (NSAID). Nimesulide works by reducing the production of free radicals that are produced during inflammation. Nimesulide also blocks neuro messengers that cause pain and inflammation in the body.

What are the uses of Nimesulide?

Nimesulide, an NSAID, has unique features of inhibiting the Cox enzyme (cyclooxygenase) that blocks the formation of prostaglandins, which leads to pain pathways. Nimesulide has analgesic, anti-inflammatory, and antipyretic properties. It, therefore, has various uses and benefits to relieve pain, inflammation, and fever. It has uses and benefits when treating:

  • Headache.
  • Backache.
  • Postoperative pain.
  • Dysmenorrhea.
  • Menstrual pain.
  • Acute pain.
  • Mild migraine.
  • Muscle pain.
  • Rheumatic Arthritis.
  • Osteoarthritis.
  • Fever.
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What are the side effects of Nimesulide?

Nimesulide should only be taken under expert medical supervision. Long-term use may affect the liver or cause serious complications such as bleeding in the stomach or kidney problems. Some common side effects that may be seen after taking Nimesulide are diarrhea, vomiting, skin rashes, itching, dizziness, bitterness in the mouth, and toxicity in the liver. You should inform your doctor before taking Nimesulide and take precautions if you have underlying problems, such as:

  • Hypersensitivity.
  • Heart failure history.
  • Liver disease.
  • Peptic ulcer.
  • Acute or chronic renal failure.

What is Nimesulide

Uses of Nimesulide

Side effects of Nimesulide


Frequently Asked Questions about Nimesulide

1. Is Nimesulide safe?

Nimesulide is safe when taken as prescribed under medical supervision or when advised by a doctor. Nimesulide can be taken through various forms, and oral form may work the best when taken for short durations. It is best to avoid it if you have any serious illnesses that are mentioned above. Speak to a medical practitioner or call our medical experts at Yashoda Hospital for a consultation.

2. Is Nimesulide safe during breastfeeding?

The action of Nimesulide on milk production for infants or the composition of milk is currently unknown. Some studies also suggest that Nimesulide is unsafe for lactating women. However, lactating women are advised to take medical expert advice, take this drug with precautions, and avoid long-term use.

3. Is Nimesulide safe during pregnancy?

Consult your doctor always before taking any medicine during pregnancy. Nimesulide being an NSAID, can alter kidney functions and is unsafe to take during later pregnancy, i.e., the last 3-months. Some past reports indicate that mothers during the trimester on Nimesulide gave birth to infants with kidney failure defects.

4. Which is better: Nimesulide or paracetamol?

Nimesulide and Paracetamol belong to the same class of medicines, and both are equally effective in reducing pain, inflammation, and fever. However, Nimesulide is not advised in children, and it is less effective if the child has inflammation in the upper respiratory tract. Nimesulide and paracetamol should not be taken together, and either medicine should be taken under expert medical advice to avoid side effects or overdose.

5. Can I take Nimesulide for a headache?

Nimesulide can be taken for a headache only when prescribed by your doctor in limited dosage. As it has a proven history of treating mild migraines, Nimesulide works best and is effective when taken for headaches as prescribed. If you have recurring headaches, this drug is not advised for long-term use, and you should consult your doctor.

6. How quickly does Nimesulide work?

Nimesulide works rapidly with immediate onset of action when taken orally. It can effectively reduce pain or fever within 15minutes of taking the medicine. For best results, it should be taken with food or milk to reduce the chances of a stomach upset. Take this medicine as prescribed by your doctor for best results.

7. Is Nimesulide safe for the kidney?

Nimesulide is an NSAID drug and is safe to use short term. When consumed long-term or in excess, Nimesulide can cause acute renal failure in individuals and can be fatal. Excess use or overdosages can provoke kidney problems or liver damage. Hence don't take this medicine without your doctor's advice.

8. How does Nimesulide work?

Nimesulide is a non-steroidal anti-inflammatory drug that inhibits the Cox-II enzyme that causes pain and inflammation. It reduces the production of free radicals that are produced by neutrophils during inflammation. It also inhibits the synthesis of platelet inhibiting factors, thereby blocking the release of messengers that causes pain and inflammation.

9. Is Nimesulide anti-inflammatory?

Yes, Nimesulide is a non-steroidal anti-inflammatory drug (NSAID). It is best known for the treatment of acute inflammation, pain, and fever. It also reduces pain and inflammation associated with certain diseases or conditions and should be taken with a doctor's prescription.

10. Which is better: Nimesulide or ibuprofen?

Ibuprofen has been used as a painkiller and as an anti-inflammatory for decades. Nimesulide is also an anti-inflammatory and analgesic drug used to treat similar conditions. However, Nimesulide overpowers Ibuprofen and has been proven to have stronger effects and provide faster results in terms of pain, fever, and inflammation. These should not be taken together as it may lead to severe complications and gastric ulcers.

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Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.