Entresto - Uses - Dosages - Side Effects - Precautions

Entresto: Frequently Asked Questions Answered

What is Entresto?

Entresto is a brand name for the drug Sacubitril/Valsartan, and it is a prescription oral medicine. It belongs to the angiotensin-neprilysin inhibitors class of drugs. This drug is used in treating heart failure and high blood pressure. The active components in Entresto are Sacubitril and Valsartan, a combination of angiotensin II receptor blocker and neprilysin inhibitor. The drug is available in tablet or suspension forms, and you should take it as per your physician’s prescription. 

What are the uses of Entresto?

Entresto minimises the risk of death resulting from heart failure. The medication is used in combination with other drugs as well. Sacubitril lowers the blood pressure in narrowing blood vessels by reducing sodium levels in the blood. Valsartan prevents blood vessel constriction and improves blood circulation.  

The drug is also effective in kids above one year. Drug dosage depends on the overall medical health, pregnancy conditions, weight and age. The doctor may initially administer a low dose before gradually increasing it.

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What are the side effects of Entresto?

The most common side effects of Entresto include:

  • low blood pressure
  • high blood potassium levels (hyperkalemia)
  • cough 
  • dizziness
  • kidney complications
  • muscle weakness
  • rashes
  • irregular breathing and heartbeat, and more. 

If you experience any of the side effects mentioned above, consult your doctor immediately. The drug can cause fatal complications to the foetus during pregnancy. It is vital to inform your doctor about possible pregnancies or family planning beforehand. If you are on medication for other comorbidities, please inform your cardiologist about the same before taking Entresto

Get a medical opinion at Yashoda Hospitals about other medications, possible pregnancy and underlying health conditions before taking Entresto


Frequently Asked Questions about Entresto

1.What time of day is best to take Entresto?

Entresto must be taken as prescribed by your doctor. Do not start or stop the medication without your doctor’s consultation. The doctor will begin with a small dosage. The dosage might be increased gradually and will have to be taken twice a day for a recommended period. The dosage will also depend upon the other medications that you are taking.

2. How long does it take for Entresto to improve ejection fraction?

An ejection fraction measures the percentage of blood pumped out from the left ventricle after contraction. Entresto efficiency varies from person to person, depending on the normal medical health, pregnancy, kidney functions and other medical histories. Naturally, it takes up to three days to see the clinical effectiveness of Entresto.

3. Can you take Carvedilol and Entresto at the same time?

Yes. You can take Entresto and Carvedilol together if your cardiologist prescribes it. Carvedilol is a beta-blocker and is usually safe when taken with Entresto because they both help lower hypertension in the blood vessels. Carvedilol or Coreg also improves the left ventricular ejection fraction.

4. Can Entresto reverse heart failure?

Entresto improves blood ejaculation and the flow rate from the heart’s left ventricle. It also dilates the blood vessels and causes hypertension. Overall, the timely administration of Entresto can increase your life expectancy, provided you do not experience massive side effects of the drug.

5. Can you drink alcohol on Entresto?

No. It’s typically recommended to avoid consuming alcohol and tobacco incase of any heart issues. The combination of Entresto and alcohol drastically lowers the blood pressure and causes heart-rhythm-related problems. If you experience any side effects of the drug, your condition may worsen with alcohol consumption.

6. Can Entresto affect your vision?

Entresto can cause various side effects in humans. It is not associated with eyesight concerns exclusively. If you are allergic to certain components in the drug, you may experience swelling around the eyes, dizziness, redness, eye irritation and numerous other cross-reactions. It is best to consult your doctor immediately for medical help.

7. Can Entresto affect your vision?

Usually, Entresto is recommended twice a day, irrespective of the dosage. It is taken once in the morning and once at night, before or after a meal as prescribed by your doctor. If you have any doubts regarding the drug, communicate freely with your doctor to get it all cleared before starting the medication.

8. What should I monitor with Entresto?

Entresto is a blood pressure drug. Once ingested, you will have to regularly monitor your blood pressure after every few hours. Besides the blood pressure, serum potassium levels should also be monitored, as the drug may cause hyperkalemia. The doctor will keep you under observation till the heart condition normalises. If the side effects persist, it is best to decrease the dosage or use other drug combinations.

9. Should Entresto be taken with food?

Entresto can be taken before or after a meal as prescribed by the doctor. Do not stop taking the drug without consulting the doctor. You can also ask your healthcare provider about a particular diet or foods that you can eat during the treatment course to clear your doubts. Confirm with your doctor which other medications you can take with Entresto to prevent further complications.

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Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.