Mebendazole, a benzimidazole, is a broad-spectrum synthetic anthelmintic medication accessible orally as chewable pills or suspension. It is particularly effective for curing the infection caused by intestinal worms. This medication, however, does not kill all types of worms; known to be effective exclusively against parasitic worms. It works by interfering with glucose metabolism and blocking microtubule polymerisation.
Mebendazole is used to treat infections caused by worms that infect the bowel (gastrointestinal tract). Acts by reducing the permeability of the cell membrane, killing the worms and curing gastrointestinal worm infection caused by pinworms, whipworms, roundworms, hookworms, and others. Adults and children over the age of 1 who have gut worm infections should take this medication only under prescription.
Mebendazole is well-tolerated in most people. Patients suffering from severe worm infestations may have –
Blood tests may show –
Particular attention to dosages and precautions is required to avoid side effects. Stop using Mebendazole and consult the doctor straight away if you notice the severe side effects. Contact our medical experts at Yashoda Hospitals for a quick consultation.
1. Which is better, Albendazole or Mebendazole?
Both Albendazole and Mebendazole are extremely successful in treating parasitic worm infection, with a cure rate of 100%. Albendazole is the recommended benzimidazole derivative for mass treatment of multiple Ascaris, hookworm, and Trichuris infections.
2. How long does Mebendazole stay in your system?
The majority of the mebendazole dosage administered orally stays in the gastrointestinal system, where it has an anthelmintic action locally. It remains in an active mode with a half-life range of 3-6 hours. Less than 2% of orally given Mebendazole is eliminated in the urine, with the balance passing through the bowels as unaltered drugs or metabolites.
3. Does Mebendazole require a prescription?
Mebendazole is an antiparasitic drug used for the treatment of worms and parasites. Although it is available as an over-the-counter drug with a non-prescription tag, it is advised to take it only under the physician's supervision.
4. How often can I take Mebendazole?
Depending on the type of worm infection, Mebendazole might be given as a single dosage or twice daily for 3days. Your doctor will advise you on how frequently to administer it. Additionally, a second treatment may be administered in a few weeks if necessary. Follow your doctor's advice for other forms of infections.
5. Is Mebendazole safe?
Mebendazole is the safest and well-tolerated antiparasitic medicine, well-effective when taken as prescribed dosages. For positive results, don't discontinue Mebendazole too soon without completing the dosage course, as your symptoms may return or worsen. Mebendazole is safe when taken with the necessary precautions to avoid side effects.
6. What drug category is Mebendazole?
Mebendazole, a benzimidazole carbamate, is one of a group of medicines called 'anthelmintics'. The pharmacologic classification of Mebendazole is benzimidazole, and the therapeutic category is anthelmintic activity.
7. Why is Mebendazole discontinued?
Mebendazole was discontinued in 2011 due to the poor tissue penetration of Mebendazole and the current availability of albendazole and not for safety or efficacy reasons, stated by the Federal Register determination. The inexpensive version of Mebendazole is no longer available, but the chewable form called Vermox or Emverm is mostly used.
8. Can Mebendazole cause liver damage?
Mebendazole is highly metabolised when taken orally, largely by the liver. Its main metabolites have greater plasma concentrations than Mebendazole. It can cause liver damage only if there is decreased hepatic function, metabolism, or biliary clearance, which can result in increased plasma concentrations of Mebendazole.
9. Does Mebendazole kill all worms?
Only parasitic worm infections or anthelmintic gastrointestinal infections caused by Ancylostoma duodenale (hookworm), Ascaris lumbricoides (roundworm), Enterobius vermicularis (pinworm), Necator americanus (hookworm), and Trichuris trichiura (whipworm) are treated with Mebendazole.
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