Mirtazapine - Uses - Dosages - Side Effects - Precautions

Mirtazapine: Frequently Asked Questions Answered

What is Mirtazapine?

Mirtazapine is a drug belonging to the antidepressant class. It treats depression arising from insomnia and anxiety. Its consumption improves balance in the brain and elevates the mood of the patient. 

Studies show that a decrease in the neurotransmitters: dopamine, norepinephrine, and serotonin causes depression in human beings. Mirtazapine helps to balance these neurotransmitters in the brain and reduce feelings of depression. It also helps manage anxiety and obsessive-compulsive disorders.

What are the uses of Mirtazapine?

Mirtazapine is an antidepressant drug that cures depression, particularly when complicated by disorders like anxiety and insomnia. It helps relieve symptoms of social anxiety disorder, depression, anxiety disorders, seasonal affective disorder, and other conditions. 

It corrects the chemical balance in the brain that causes symptoms of depression. The medicine helps elevate the mood and feelings of a patient. It rapidly mitigates depressive symptoms in depressed and anxious patients, along with melancholic, treatment-resistant, and geriatric depression. It can also improve symptoms of depression related to alcohol dependence.

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What are the side effects of Mirtazapine?

Mirtazapine may not suit everybody. Some of the usual side effects include:

  • Sleepiness.
  • Constipation.
  • Increased appetite.
  • Weight gain.
  • Dry mouth.
  • Dizziness.

Some severe side effects of Mirtazapine can include:

  • Sleep trouble.
  • Chills.
  • Mood swings.
  • Reckless behavior.
  • Aggressive or violent thoughts.
  • Fever.
  • Vomiting.
  • High blood pressure.
  • Nausea.
  • Hallucinations.
  • Sore throat.
  • Irregular heartbeat.

Take necessary precautions, such as talking to the doctor about your medical history before taking Mirtazapine. The usual side effects go away with some time. If you experience severe side effects, consult a doctor immediately.

S.no Product Name Dosage Form
1. Mirawin Mirtazapine 15mg Tablet
2. Mizadep MD Mirtazapine 15mg Tablet
3. Depel Mirtazapine 15mg Tablet
4. Mirsol Mirtazapine 30mg Tablet
5. Mitrazac Mirtazapine 15mg Tablet


Frequently Asked Questions about Mirtazapine

1. Is Mirtazapine an SSRI?

No, Mirtazapine is not an SSRI. An SSRI is an antidepressant drug that inhibits the reabsorption of serotonin by neurons. It allows serotonin to be available as a neurotransmitter. However, it is a NaSSA that enhances the release of norepinephrine and serotonin transmission. This dual mechanism helps Mirtazapine to act rapidly and show positive results.

2. How long does Mirtazapine take to work for sleep?

Sleeping problems and depression are closely linked. On consumption, Mirtazapine takes one to two weeks before improving sleep, energy, and appetite. It reduces the time a patient takes to fall asleep and the duration of early stages of sleep. Mirtazapine increases deep sleep by reducing dream sleep (REM) and night-time waking.

3. Is Mirtazapine a controlled substance?

No, Mirtazapine is not a controlled substance. It doesn’t cause physical or mental dependence or addiction. Controlled substances are prescription drugs for which manufacturing and possession are tightly governed and regulated because they cause significant levels of dependency. The five classes of controlled substances are narcotics, hallucinogens, depressants, stimulants, and anabolic steroids.

4. Does Mirtazapine cause weight gain?

Yes, Mirtazapine can cause weight gain in some patients. One common side effect of Mirtazapine includes increased appetite, resulting in significant weight gain. Some patients show a noticeable rise in fat mass, weight, and leptin concentration in the body. However, this does not apply to all patients consuming Mirtazapine.

5. How does Mirtazapine work?

Mirtazapine is an antidepressant that manages depression. On consumption, it increases the activity of mood-elevating neurotransmitters in the body. It helps increase levels of dopamine, norepinephrine, and serotonin in the body. You will see positive results in a week or two. However, it takes four to five weeks before absolute results are achieved.

6. Can you overdose on Mirtazapine?

Overdose of Mirtazapine can be harmful and lead to a medical emergency. Always take the dosages and precautions with Mirtazapine according to a doctor’s consultation. If you overdose on it, there are chances of severe side effects on your body’s functions. You might experience overdose symptoms like memory problems, confusion, fast heart rate, and drowsiness.

7. How long does Mirtazapine stay in your system?

Mirtazapine usually stays for four to nine days in your body. Various factors like age, genetics, dosage, liver and kidney function, and drug history decide the time your body will take to clear Mirtazapine. It has a half-life of 20–40 hours. Your system will excrete most of the medication within five days after the last dosage.

8. Does Mirtazapine help with anxiety?

Yes, Mirtazapine helps to cure several anxiety disorders as well. Anxiety happens when there is an imbalance in neurotransmitters like serotonin, norepinephrine, dopamine, and gamma-aminobutyric acid in the brain. Mirtazapine helps to improve mood, resulting in improved sleep. It usually takes a week or two to see positive results. You will experience complete results after four to five weeks.

9. Is Mirtazapine a benzodiazepine?

Mirtazapine is a tetracyclic antidepressant that treats severe depressive disorders. It is not a benzodiazepine drug. Benzodiazepines are psychoactive drugs that help to treat anxiety, seizures, and insomnia. As both drugs sound and function similarly, it’s crucial to consult a doctor before consuming any of them.

10. Does Mirtazapine calm you down?

Yes, Mirtazapine has a sedating effect that helps you calm down. Neurochemical imbalances in the brain cause depression and anxiety. Mirtazapine helps balance serotonin and norepinephrine that help with relaxation and calmness. It reduces stress and anger by rapidly boosting your mood and happy feelings in the brain.

11. Is Mirtazapine a strong antidepressant?

Mirtazapine is a new class of antidepressants that has a rapid onset of action on depressive symptoms. Its dosage is highly effective in treating moderate to severe depression and anxiety disorders. It enhances the balance of neurotransmitters that calms you down. In four to five weeks, you will observe and experience definite results.

You can consult our doctors at Yashoda Hospitals if you are dealing with depression or anxiety issues. Our doctors are just an appointment away to help you bid farewell to your problems.



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      Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.