Entyvio - Uses - Dosages - Side Effects - Precautions

Entyvio: Frequently Asked Questions Answered

What is Entyvio (vedolizumab)?

Vedolizumab, which is sold under the brand name of Entyvio, belongs to a class of drugs known as monoclonal antibodies. The medication works by blocking the action of some natural substances in the body. Entyvio is administered for the treatment of ulcerative colitis and Crohn’s disease. In these medical conditions, the body’s immune system attacks the healthy cells in the gut, which leads to a range of symptoms such as diarrhoea, abdominal pain and blood in the stool.

What are the uses of Entyvio?

Entyvio (vedolizumab) is a monoclonal antibody that is used as a prescription drug for the treatment of moderate or severe ulcerative colitis and severe Crohn’s disease. These conditions can cause adverse gut-related symptoms such as vomiting, nausea, diarrhoea, abdominal pain, and blood in the stool. Entyvio reduces the effect of certain symptoms that aggravate these conditions. 

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What are the side effects of Entyvio?

Some of the side effects of Entyvio are as follows: 

  • Nausea
  • Headache 
  • Fatigue
  • Cold and flu 

You should consult your doctor immediately if any of these symptoms get worse and also consult our experts for a medical opinion. 


Frequently Asked Questions about Entyvio

1. How long does Entyvio take to work effectively?

Entyvio typically becomes effective 4-6 weeks after starting the medications. The effectiveness, however, varies from person to person. It can take up to 14 weeks to reduce symptoms, and in some cases, patients do not respond to the drug at all. Sometimes, patients may notice a gradual improvement in their symptoms within the first week of taking Entyvio.

2. Does Entyvio weaken the immune system?

Entyvio is not a systemic immunosuppressant drug and does not affect the whole body. It has a selective effect on the gut, wherein the symptoms are observed. Entyvio prevents white blood cells from entering the gastrointestinal tract. That’s the basic principle behind how the medication works. It inhibits inflammation and other abdominal symptoms.

3. Can Entyvio make you lose weight?

Clinical trials suggest that weight loss is not a side effect of Entyvio. However, gastric conditions such as colitis and Crohn’s disease can cause stomach cramps, nausea, diarrhoea and loss of appetite, which can lead to weight loss. This can be managed through a proper diet. Consult a doctor to get more information on this.

4. How do you feel after an Entyvio infusion?

You will not experience an immediate effect of the drug on your symptoms. However, severe allergic reactions are known to occur in people who suffer from allergies during or after the injection is given. If you experience a severe reaction, the drug should be stopped immediately. Contact your doctor to explore suitable alternatives.

5. Can you drive after an Entyvio infusion?

Few patients have reported mild dizziness after taking Entyvio which can affect the ability to drive or use heavy machines. It’s recommended to avoid driving if you experience dizziness after taking the drug.

6. Does Entyvio cause coughing?

A persistent cough can be a potential side effect of Entyvio injection. The cough can also be accompanied by flu-like symptoms such as a runny nose, fever, chills and body aches. You should consult your doctor immediately if you experience severe side effects after taking the medication.

7. Does Entyvio need to be refrigerated?

Yes, Entyvio should be stored in the refrigerator at a temperature between 2 and 8 degrees celsius. The drug should not be frozen because this can affect its chemical properties and lead to inefficacy. Keep the drug away from light and store injection vials in their original packaging. Proper storing conditions are essential.

8. Does Entyvio make you feel tired?

Yes, Entyvio can also make you feel tired, cause fatigue or lack of energy. This can also be accompanied by body aches and general dullness during the day. However, this is a temporary side effect, which can be improved through diet and hydration. Please consult a doctor to know more.

9. Does Entyvio affect blood pressure?

Flushing, headache and high blood pressure are unusual side effects of Entyvio. If a patient's blood pressure rises after taking the medication, this should be reported to his or her doctor right away. If the patient has always had high blood pressure, he or she should seek alternative treatment, as directed by the doctor, because Entyvio can aggravate the condition. High blood pressure, as well as skin rashes and breakouts, are common symptoms of an allergic reaction to Entyvio injection. Before taking the medication, the patient must inform the doctor about any underlying conditions.

10. Can Entyvio cause mood swings?

While mood swings are not a direct side effect of Entyvio, other side effects can involve a feeling of dullness, moodiness and lethargy in the patient. Acute depression due to Entyvio is rare. However, consult your doctor immediately if you experience chronic mood swings. Get an online consultation from our team of expert doctors at Yashoda Hospitals.

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Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.


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