Acute Kidney Injury with Hemoptysis – A Formidable Challenge for a Clinician

Granulamatosis with polyangitis (GPA), previously known as Wegner’s granulamatosis is one of the three ANCA associated vasculitis. The pathogenesis involves an environmental trigger in a genetically susceptible individual resulting in the production of pathogenic antibodies, antineutrophil cytoplasmic antibodies (ANCAs), leading to necrotising small and medium vessel vasculitis.

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