Kidney Transplants – Diseases & Conditions
Kidney transplants for Kidney diseases & Kidney failure
Kidney diseases and injuries can affect how kidneys function. Over a period of time, untreated kidney diseases can result in slow and silent decline in kidney function. Some of the diseases such as diabetic kidney disease, blood pressure, glomerular diseases, congenital kidney diseases, trauma or poisoning can cause damage to the nephrons, the filtering units of kidneys, and thus reduce the kidney function or renal function.
Kidneys are a pair of bean-shaped organs each roughly measuring a size of a fist. Kidneys process about 180 liters of blood and remove almost 2 liters of waste every day. Renal function: When both the kidneys are functioning normal. Kidneys are made of small filtering units called nephrons, a group of tiny blood vessels called glomerulus connected to a urine collecting tubule. The glomerulus plays a major role in retaining normal proteins, blood cells and allowing only extra fluid and wastes into the tubule. An intact electrolyte balance and complex chemical exchanges ensure the kidneys function of regulating fluid levels, blood pressure, and calcium & other electrolyte levels in the blood.
Renal function or Kidney function is intact when both the kidneys are working efficiently as measured by estimated glomerular filtration rate (eGFR). eGFR is the measure of percentage of kidney function that is available. Rarely, small or mild decline (30 to 40%) is noticed even in normal individuals. People with reduced kidney function usually have an associated kidney disease and there are chances of both of them worsening with age. Kidney diseases and decline in kidney function are usually silent, until the decline is severe with an eGFR of 25%. Any further decline below 10 – 15% requires lifetime dialysis or renal transplant or dialysis.
Some of the common diseases with associated kidney failure are:
- Acute kidney injury (AKI): A sudden injury and resulting sudden drop in functions of kidneys due to infection or trauma or accident is called acute kidney injury. Sometimes the damage to the kidneys is reversible, thus it is also called as acute renal failure. However, AKI may lead to permanent loss of kidney functions.
- Chronic kidney disease (CKD): A longstanding trigger or a health condition can cause slow, silent deterioration of kidney functions. The gradual loss of kidney function is called as chronic kidney disease of chronic renal insufficiency. The eGFR falls below 60 for 3 months or longer in patients with CKD. Over a period of time, further decline & serious damage to the kidneys cause complications. Patients with CKD are at a greater risk of heart conditions, stroke and even death.
- End-stage renal disease (ESRD): End-stage renal disease is a disease characterized by permanent, total or near total kidney failure. As a result, the body retains water and waste materials causing the hands/feet to swell. The condition is called as uremia, which can result in seizures or coma when untreated. Immediate and routine dialysis or kidney transplantation then becomes very essential.
It is important that patients with kidney diseases take control of their health. There is no cure for chronic kidney disease (CKD) and end-stage renal disease (ESRD). However, a prompt action plan goes a long way to delay the progress, reduce complications such as stroke, heart attack. People with reduced kidney function should:
- Visit their doctor/nephrologist regularly.
- Keep a close tab on vitals such as blood glucose levels & blood pressure and take steps to prevent anemia of renal failure.
- Avoid pain relief pills that may worsen kidney diseases. They should check with their healthcare provider before taking any medicine.
Health Blogs for Kidney
Frequently asked questions about kidney transplant
May 04, 2019 11:25
Kidney transplant refers to a surgical procedure of placing a healthy kidney from a donor (alive or deceased) in the body of an individual whose kidneys fail to function normally. Kidney transplant is one of the most common transplant surgeries done around the world.
మూత్రపిండాల సమస్యలను గుర్తించటం ఎలా ? చికిత్స విధానాల వివరాలు
Mar 29, 2019 16:02
మూత్రపిండాల సమస్యలో ఐదు దశలు ఉంటాయి. మొదటి దశ, రెండో దశలో అసలు వ్యాధి లక్షణాలు కనిపించవు. మూడో దశలో ఆకలి మందగించడం, నీరసం, ముఖం వాచినట్లుగా ఉండటం, కాళ్లలో వాపు రావడం వంటి లక్షణాలు కనిపిస్తాయి.
వేసవిలో వేధించే మూత్రనాళ, కిడ్నీ వ్యాధులు ముందు జాగ్రతతో ఉపశమనం, ప్రమాదకర సమస్యల నివారణ
Mar 12, 2019 17:04
ఎండకాలం వచ్చే ఆరోగ్యసమస్యలలో మూత్రపిండాలు, మూత్రసంబంధమైనవి ముందు స్థానంలో ఉంటాయి. వీటిలో మూత్రపిండాలలో రాళ్లు ఏర్పడటం, యూరినరీ ట్రాక్(మూత్రనాళపు) ఇన్ఫెక్షన్లు ప్రధానమైనవి.
Learn the facts about PKD – Polycystic Kidney Disease
Mar 09, 2019 13:16
Polycystic kidney disease is characterised by cysts in the kidney which increase both in size and number, often resulting in kidney failure. Kidney transplant has shown successful result but precautionary measures are to be taken to cope up with its complications.
Hemolytic Uremic Syndrome (HUS)
Sep 19, 2016 07:00
A type of E. coli bacteria produces toxins that can destroy the red blood cells and block the kidneys’ filtering system Hemolytic uremic syndrome (HUS) is a condition where the red blood cells are destroyed, abnormally. This leads to clogging of the kidney’s filtering system and leads to kidney failure. Hemolytic uremic syndrome (HUS) is […]
Chronic Kidney Disease (CKD)
Sep 03, 2016 05:37
Chronic kidney disease or chronic kidney failure is a slow and progressive loss of kidney function over a period of several years Chronic kidney disease (CKD) also described as chronic kidney failure is a condition where kidneys gradually stop functioning. The primary function of kidneys is to filter wastes and excess fluids from the blood. […]
Age-related Kidney Diseases
Aug 16, 2016 07:09
Anyone can develop kidney disease, regardless of the age Kidney diseases may occur in all age groups. Except for the hereditary link, in many instances kidney diseases may have been caused by an underlying disease. Glomerulonephritis is a condition where the kidneys get inflammated / swollen. Diabetes (excess sugar in the blood) is one of […]
Acute kidney failure – loss of kidney’s filtering ability
May 11, 2016 04:59
Acute kidney failure is a condition where the kidneys no longer filter the waste products from the blood. This condition results in accumulation of waste in the blood leading to further complications. Acute kidney failure may happen over few hours or days, and usually seen in patients undergoing treatment for kidney diseases. Acute kidney failure […]
Towards innovation – Continuous Renal Replacement Therapy (CRRT)
Dec 17, 2015 08:51
Continuous renal replacement therapy or CRRT is a blood purification therapy. CRRT is advised for patients suffering from impaired renal function, also referred to as Acute Kidney Injury (AKI). ICU patients undergo this therapy 24 hours a day. Kidney failure or renal insufficiency is a medical condition in which the kidneys fail to adequately filter […]