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Ultra-Low Contrast Angiography

What is Ultra-Low Contrast Angiography?

Ultra-low contrast angiography is a novel technique performed in interventional cardiology and nephrology that utilizes new intravascular invasive technology and non-invasive contrast-sparing techniques. There are two types: ultra-low contrast percutaneous coronary intervention (ULC-PCI) and zero-contrast PCI. 

A primary objective of ultra-low-contrast angiography is to minimize contrast exposure and potentially use the least toxic contrast agents to reduce the risk of developing postprocedural contrast-induced nephropathy (CIN), predominantly affecting patients with baseline systemic dysfunctions.

How is Ultra-Low Contrast Angiography performed? 

Here are some techniques used during ULC angiography, including: 

 

  • Low-osmolar contrast medium for clear imaging. 
  • Intravascular ultrasound for imaging guidance and to reduce the contrast load. 
  • Intravenous volume hydration reduces the contrast concentration and increases the blood flow. 
  • Using small volumes of contrast dye with small catheters to improve visualization. 
  • Using multiple guide wires, such as the side branch wire, the marking wire technique. 
  • Using coronary calcium as the guideline to locate and trace coronary artery ostia. 
  • Increase frame rates to 30 frames per second or higher for improved visualization.

Advantages of Ultra-Low Contrast Angiography

 

  • Affordable, effective, and safe in various clinical settings. 
  • Reduced the risk of contrast-induced nephropathy. 
  • Minimizes the need for large volumes of contrast injections. 
  • Time-efficient procedure. 
  • Visualizes even subtle calcifications on the vascular wall. 
  • Imaging can be performed from multiple directions. 

Clinical Indications for Ultra-Low Contrast Angiography 

 

  • Patients with pre-existing chronic kidney disease. 
  • Cardiogenic shock.
  • Contrast dye anaphylaxis. 
  • Complex, high-risk coronary disease. 
  • Iatrogenic or spontaneous coronary dissection. 
  • Chronic total occlusions. 

Our goal is to preserve the patient’s quality of life through intricate, minimally invasive, and non-invasive methods and preserve the patient’s well-being. Explore our advanced angiography techniques and get affordable treatment options today!