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« Diseases » Interstitial_keratitis
 
Interstitial keratitis
Eye
Eye

Alternative names 

Keratitis interstitial

Definition 

Inflammation of the connective tissue structure of the cornea (the clear window on the front of the eyeball). interstitial keratitis is a serious condition which may cause severe visual impairment. blood vessels grow into the cornea and cause loss of the normal transparency. it is caused by infectious diseases. syphilis is the most common cause, but other rare causes include leprosy and tuberculosis.

Causes and risks

Most cases in the developed world occur in patients with fully established systemic infection with the spirochete of syphilis. Since most cases of syphilis are recognized and treated, it is not common. Interstitial keratitis is the most common cause of blindness in the world, with cases caused by trachoma and onchocerciasis (river blindness) being very common in endemic areas of Asia and Africa.

Prevention

Prevention consists of avoidance of the underlying infection; and if infected, prompt and thorough treatment and follow up.

Symptoms

  • eye pain
  • photophobia
  • excessive tearing

Signs and tests 

Interstitial keratitis can be easily diagnosed by physical examination of the eyes with slit lamp examination. Blood tests and chest x-rays will usually be needed to find and prove the causative infection.

Treatment

The underlying disease must be treated. Treatment of the cornea with corticosteroid drops may minimize scarring and help preserve the clarity of the cornea.

Prognosis

If interstitial keratitis is diagnosed early and treated effectively, the corneal clarity and thus good vision will be preserved.

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